Results Of 826 women, mean age at diagnosis was 36.1 years most women were White non-Hispanic (86.7%). Main Outcomes and Measures Physical functioning, body image, sexual health, anxiety and depressive symptoms were assessed in follow-up. Participants Women age ≤40 when diagnosed with Stage 0-3 with unilateral breast cancer between 20 who had surgery and completed QOL and psychosocial assessments.Įxposures (for observational studies) Primary breast surgery including breast-conserving surgery (BCS), unilateral mastectomy (UM), and BM. Setting Multicenter, including academic and community hospitals in North America Objective To evaluate the differential associations of surgery with quality of life (QOL) and psychosocial outcomes from 1 to 5 years following diagnosis.ĭesign, Setting, and Participants Cohort study Importance Young women with breast cancer are increasingly choosing bilateral mastectomy (BM), yet little is known about short-term and long-term physical and psychosocial well-being following surgery in this population. Health-related quality of life following breast reconstruction compared to total mastectomy and breast-conserving surgery among breast cancer survivors: a systematic review and meta-analysis. Zehra S, Doyle F, Barry M, Walsh S, Kell MR. Association of breast cancer surgery with quality of life and psychosocial well-being in young breast cancer survivors. Rosenberg SM, Dominici LS, Gelber S, Poorvu PD, Ruddy KJ, Wong JS, Tamimi RM, Schapira L, Come S, Peppercorn JM, Borges VF, Partridge AH.
In addition, the effect of QOL on the prognosis in patients with breast surgery should be specified in study by Rosenberg et al.ġ. differentiated patients into UM and BM, and there is a possibility of the difference in HR-QOL within M group, which should be checked by further studies. As there was a significant heterogeneity in most BR versus BCS outcomes, further studies are needed to compare HR-QOL in patients with BR and BCS groups. In contrast, there were no significant difference in social health, emotional health, global health, and sexual health between BR/BCS groups and M group. HR-QOL outcomes such as physical health and body image in BR and BCS groups were better than the M group. reviewed sixteen studies with BR, BCS or M groups (2). I present a recent meta-analysis on health-related QOL (HR-QOL) following BR, BCS or mastectomy (M). In contrast, there were minimal between-group differences in depression levels in follow-up. Young breast cancer survivors who undergo more extensive surgery had worse body image, sexual health, and anxiety compared with women undergoing less extensive surgery. Of women who had BM/UM, 84% had reconstruction (BR). Regarding surgery, 45% had BM, 31% BCS, and 24% UM. The authors selected primary breast surgery including breast-conserving surgery (BCS), unilateral mastectomy (UM), and bilateral mastectomy (BM). conducted a prospective study to evaluate the differential associations of surgery with quality of life (QOL) and psychosocial outcomes in women age ≤40 when diagnosed with Stage 0-3 with unilateral breast cancer (1).
Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.
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